These direct trains from Bern to Frankfurt (Main) can offer a swathe of straightforward connections on to other German cities without direct trains from Bern, including Dresden, Leipzig and Nurnberg
3 x direct trains per day
Book early and save: Yes
When making an online booking, check that you’re looking at booking info for the direct trains.
On the DB Bahn booking site look for journeys that have:
Reservations are highly recommended for this journey; book a 1st class ticket and your seat will be assigned, but not if you book 2nd class - or will be travelling with a rail pass.
Every other hour during the ICE day trains depart Basel for Frankfurt (Main) so the most straightforward option for an end-to-end journey when the timings of the direct trains don't suit is to take one of the two trains per hour from Bern to Basel, in order to connect into these trains.
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